Breast Cancer Drug Linked to Brain Malfunction
Thursday, December 27, 2018 IST
The drug letrozole is used to prevent breast cancer recurrence by interfering with the production of estrogens.
A breast cancer drug reveals side-effects, including mood disturbances and memory issues, that impact the brain function in both humans and animals, say researchers.
The drug letrozole is used to prevent breast cancer recurrence by interfering with the production of estrogens.
For the study, researchers from the University of Toronto in Canada showed that they administered letrozole to male and female marmosets -- a nonhuman primate model -- for four weeks and observed many behavioural changes including hot flashes and increased anxiety, experienced by women receiving similar treatment.
In addition, letrozole also compromised the function of neurons in the hippocampus (organ located in the brain) and impaired spatial memory, results revealed, published in the Journal of Neuroscience.
Findings emphasise the need for further investigation of breast cancer treatments and their effects on the brain, the team noted.
Breast cancer is the top cancer in women worldwide and is increasing particularly in developing countries where a majority of cases are diagnosed in late stages.
Related Topics
Trending News & Articles
Lung cancer is usually not noticeable during the early stages. Most people are diagnosed when the disease is at an advanced stage. According to Cancer.org, it is ...
Recently posted . 9K views . 2 min read
The health benefits of wood apple include [1] relief from constipation, indigestion, peptic ulcer, piles, respiratory problems, diarrhea, and dysentery. It also b...
Recently posted . 6K views . 2 min read
The scientists likewise shared how much liquor an individual can drink prior to facing overabundance risk challenges their wellbeing, contrasted with somebody who...
Recently posted . 6K views . 1 min read
Bael, also known as the “Wood Apple”, is a species native to India. The bael tree is considered to be sacred to the Hindus. A famous drink known as sh...
Recently posted . 6K views . 2 min read
More in Food & Health
We have all heard the age-old adage “an apple a day keeps the doctor away” at one time or another. And, it turns out that there is a fair bit of truth...
Recently posted. 1K views . 1 min read
Breast cancer in men is very rare, with only one chance in one thousand (1/1000) of diagnosis. Even so, breast cancer in men is just as serious as that which wome...
Recently posted. 3K views . 2 min read
Starbucks goes upscale with $10 coffee Starbucks goes upscale with $10 coffee
Starbucks sees food innovation and its cold espresso beverag...
Recently posted. 989 views . 30 min read
Recently posted . 1K views
Recently posted . 1K views
Recently posted . 2K views
Recently posted . 2K views
Recently posted . 2K views . 76 min read
Recently posted . 2K views . 34 min read
Studies show that a third of US adults do not get their proper sleep. It’s not news that lack of sleep will cause terrible problems to your body. Adults are s...
Recently posted. 1K views . 1 min read
The word yoga comes from the Sanskrit word for yoke, “yuji.” It is an activity that has been practised since ancient times and is used as a way to focus...
Recently posted. 1K views . 1 min read