Breast Cancer Drug Linked to Brain Malfunction
Thursday, December 27, 2018 IST
The drug letrozole is used to prevent breast cancer recurrence by interfering with the production of estrogens.
A breast cancer drug reveals side-effects, including mood disturbances and memory issues, that impact the brain function in both humans and animals, say researchers.
The drug letrozole is used to prevent breast cancer recurrence by interfering with the production of estrogens.
For the study, researchers from the University of Toronto in Canada showed that they administered letrozole to male and female marmosets -- a nonhuman primate model -- for four weeks and observed many behavioural changes including hot flashes and increased anxiety, experienced by women receiving similar treatment.
In addition, letrozole also compromised the function of neurons in the hippocampus (organ located in the brain) and impaired spatial memory, results revealed, published in the Journal of Neuroscience.
Findings emphasise the need for further investigation of breast cancer treatments and their effects on the brain, the team noted.
Breast cancer is the top cancer in women worldwide and is increasing particularly in developing countries where a majority of cases are diagnosed in late stages.
Related Topics
Trending News & Articles
Lung cancer is usually not noticeable during the early stages. Most people are diagnosed when the disease is at an advanced stage. According to Cancer.org, it is ...
Recently posted . 9K views . 2 min read
The health benefits of wood apple include [1] relief from constipation, indigestion, peptic ulcer, piles, respiratory problems, diarrhea, and dysentery. It also b...
Recently posted . 6K views . 2 min read
The scientists likewise shared how much liquor an individual can drink prior to facing overabundance risk challenges their wellbeing, contrasted with somebody who...
Recently posted . 6K views . 1 min read
Bael, also known as the “Wood Apple”, is a species native to India. The bael tree is considered to be sacred to the Hindus. A famous drink known as sh...
Recently posted . 6K views . 2 min read
More in Food & Health
In recent years we've seen some neat re-thinks of basic cookware, from a self-stirring pot to Mike Whitehead's CNC-milled cast iron skillet. Now a rocket sc...
Recently posted. 1K views . 1 min read
A new study suggests that wellness programs at the workplace usually benefit people who are already health conscious and are more likely to enroll in them and mak...
Recently posted. 939 views . 1 min read
Consuming water in the morning as soon as you wake up is beneficial for many health problems from fatigue and pain to cancer and asthma.
Recently posted. 1K views . 0 min read
Recently posted . 1K views
Recently posted . 1K views
Recently posted . 2K views
Recently posted . 2K views
Recently posted . 2K views . 155 min read
Recently posted . 2K views . 45 min read
New Delhi: Malaria is an existence debilitating mosquito-borne sickness that is transmitted to individuals through the nibbles of contaminated female Anopheles mosq...
Recently posted. 1K views . 20 min read
Whether the goal is to prevent a hangover, limit calorie intake, or throw caution to the wind for an all-out rager, many drinkers follow a set of time-honored rul...
Recently posted. 1K views . 2 min read