Purdue University researchers detect new Zika virus structure

In a step that would help better understand how the Zika virus infects host cells and spreads, researchers have discovered a new structure of the deadly virus.

Researchers from Purdue University analysed the high-resolution structure of the immature form of the Zika virus.

The research team found that the immature Zika virus had a similar structure to other related viruses, such as the West Nile virus and dengue fever.

The team of study led by Michael Rossmann and Richard Kuhn, both professors in Purdue's Department of Biological Sciences, comprised of postdoctoral research associate Vidya Mangala Prasad.

It is, therefore, probable that the immature form of Zika also plays a role in virus infection and spread," said Michael Rossmann.

Zika belongs to a family of viruses called flaviviruses, which includes dengue, West Nile, yellow fever, Japanese encephalitis and tick-borne encephalitis viruses.

The study suggests that while only the mature forms of flaviviruses are considered infectious, the virus population secreted from host cells is a mixture of mature, partially mature and immature virus particles.

I think these findings open the door to begin to explore the assembly process of the virus," said Richard Kuhn, director of the Purdue Institute for Inflammation, Immunology and Infectious Diseases, in the release. "We see clear differences between the structure of the immature virus and the mature virus. Not only are there differences in the outer structure, but the inner core must also undergo some significant changes during maturation. We need to study what these changes are and why they occur."

To determine the molecular structure, the team used a technique called cryo-electron microscopy, which allowed the researchers to observe the virus at a resolution of 9 Ångstroms, a high enough resolution to note tiny structural details.

Zika virus has been linked with microcephaly – a birth defect - which causes babies to be born with abnormally small heads and also with the autoimmune disorder Guillan-Barré syndrome.

Italian Doctor Claims :Cancer is a fungus that can be eliminated with baking soda

New Delhi: Cancer is a standout amongst the most alarming illnesses that humanity needs to manage. Maybe, the very idea of being determined to have cancer can be wrecking as it is an occasion that runs as one with dread and endless supply of the illness, trailed by rounds of chemotherapy and medicines.

While not each determination brings about an end of the casualty, enough of them do as such, for the most part, due to an absence of familiarity with cancer, which prompts delay in discovery of the infection.

Notwithstanding when analyzed and treated early, cancer still has a sensible opportunity to murder the patient.

As per the World Health Organization (WHO), cancer is the second driving reason for death all around, and was in charge of 8.8 million passings in 2015. Comprehensively, almost 1 in 6 passings is because of cancer.

Cancer is a gathering of sicknesses in which unusual cells isolate wildly and spread to different parts of the body. It emerges from the change of ordinary cells into tumor cells in a multistage procedure that by and large advances from a pre-cancerous sore to a harmful tumor.

Be that as it may, for this Italian specialist, cancer is only a parasite which can be disposed of with baking soda.

"About a century prior, there was an awesome hypothesis that cancer is caused by failing qualities, which implies that the sickness is intracellular. Nonetheless, as I would see it, cancer is a parasitic contamination and an uncommon cell marvel," Dr Tulio Simonchini, who has sent shockwaves around the medicinal group with his claim, was cited as saying.

Dr Simonchini said he utilized this technique for over 20 years to cure a large number of patients experiencing diverse sorts of cancer, and guaranteed that it is 100% successful.

As per Dr Simonchini, the difficult reality of more cancer cases is by one means or another associated with the disappointments of oncology.

"We need to demonstrate that cutting edge oncology can't answer every one of the inquiries cancer patients have. It's our good and moral sense of duty regarding locate the genuine cure for the hardest and deadliest illnesses of our time," he included.

Much the same as parasitic contaminations cause carcinoma in the plant world, Dr Simonchini trusts an indistinguishable occurs in people from well. He supposes growths make cancer, debilitate our insusceptible framework and afterward assault the entire body.

Dr Simonchini additionally asserts cancer is a "ulcer" where twisted cells aggregate and shape provinces.

So the most ideal approach to dispose of a tumor, as indicated by Dr Simonchini, is for it to interact with baking soda, which can be connected as a douche for stomach related cancers, intravenous infusion for mind and lung tumors and inward breath for tumors in the upper respiratory framework.

For breast, lymph framework and subcutaneous tumors, he said they can be treated with a neighborhood perfusion.

He said inward organ tumors ought to be treated with baking soda by applying it specifically into the supply routes, while additionally alerted that it's likewise essential to treat each kind of cancer with the best possible measurement.