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Purdue University researchers detect new Zika virus structure
Food & Health   Tuesday, January 10, 2017 IST
 
Purdue University researchers detect new Zika virus structure

Purdue University researchers detect new Zika virus structure

In a step that would help better understand how the Zika virus infects host cells and spreads, researchers have discovered a new structure of the deadly virus.

Researchers from Purdue University analysed the high-resolution structure of the immature form of the Zika virus.

The research team found that the immature Zika virus had a similar structure to other related viruses, such as the West Nile virus and dengue fever.

The team of study led by Michael Rossmann and Richard Kuhn, both professors in Purdue's Department of Biological Sciences, comprised of postdoctoral research associate Vidya Mangala Prasad.

It is, therefore, probable that the immature form of Zika also plays a role in virus infection and spread," said Michael Rossmann.

Zika belongs to a family of viruses called flaviviruses, which includes dengue, West Nile, yellow fever, Japanese encephalitis and tick-borne encephalitis viruses.

The study suggests that while only the mature forms of flaviviruses are considered infectious, the virus population secreted from host cells is a mixture of mature, partially mature and immature virus particles.

I think these findings open the door to begin to explore the assembly process of the virus," said Richard Kuhn, director of the Purdue Institute for Inflammation, Immunology and Infectious Diseases, in the release. "We see clear differences between the structure of the immature virus and the mature virus. Not only are there differences in the outer structure, but the inner core must also undergo some significant changes during maturation. We need to study what these changes are and why they occur."

To determine the molecular structure, the team used a technique called cryo-electron microscopy, which allowed the researchers to observe the virus at a resolution of 9 Ångstroms, a high enough resolution to note tiny structural details.

Zika virus has been linked with microcephaly – a birth defect - which causes babies to be born with abnormally small heads and also with the autoimmune disorder Guillan-Barré syndrome.



 
 
Natural Remedies for Defeat Malaria at Home
Food & Health   Tuesday, January 10, 2017 IST
 
Natural Remedies for Defeat Malaria at Home

Natural Remedies for Defeat Malaria at Home

New Delhi: Malaria is an existence debilitating mosquito-borne sickness that is transmitted to individuals through the nibbles of contaminated female Anopheles mosquitoes.

Regardless of gigantic advance, malaria claims 429,000 lives every year, with the majority of them kids, and causes 212 million new cases internationally. Along these lines, malaria stays one of the world's most unyielding wellbeing challenges.

In spite of the fact that malaria is fatal, it is preventable and treatable. Vector control is the fundamental approach to counteract and diminish malaria transmission. Two types of vector control: bug spray treated mosquito nets and indoor remaining showering are successful in an extensive variety of conditions.

Additionally, there are various compelling ways and common solutions for treat intestinal sickness fever. These include:

Citrus fruits

Citrus natural products, for example, limes and lemons are prescribed for treating malaria. The cell reinforcement mixes, vitamins, and minerals in citrus organic products can help take out a fever, keep the ascent of temperature and disease and also accelerate the recuperating procedure.

Grapefruit

Grapefruit is an extraordinary homegrown solution for malaria because of the nearness of a characteristic quinine-like substance that has been straightforwardly connected to killing those intestinal sicknesses initiating parasites. Different natural products like oranges and apples are likewise useful in treating intestinal sickness patients.

Holy Basil

The dynamic fixing called eugenol found in sacred basil is to a great extent in charge of its restorative properties that can help kill bacterial contaminations. For a long time, blessed basil leaves are viewed as an incredible natural solution for different ailments, and malaria is one of them.

Ginger

Stacked with supplements and bioactive intensifies that have capable advantages for your body and cerebrum, ginger is an extraordinary characteristic home cure and among most advantageous flavors on the planet. Ginger has been utilized for treating different sicknesses, going from colds to bringing down cholesterol levels and forestalling disease. Ginger is likewise observed to be powerful while curing the issue of intestinal sickness.

Cinnamon

A complete cure, cinnamon contains an effective natural segment called cinnamaldehyde, which has mitigating properties and has been connected to a decrease in malaria side effects.

Today, the 25th of April, is World Malaria Day, an event to highlight the requirement for proceeded with speculation and maintained political responsibility for intestinal sickness anticipation and control. The current year's worldwide subject for World Malaria Day is 'End Malaria for Good'.



 
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